Impaired Renal Function

We collaborate directly with Dr. Vincent Pichette, M.D., Ph.D. Nephrologist, and have access to over 1,300 patients with mild, moderate and severe renal function impairment, as well as patients requiring dialysis.

Impaired Renal Function

Algorithme Pharma's Patient Access

  • 1300 + patients with mild, moderate and severe renal function impairment, and patients requiring dialysis
  • Strategic alliance with HMR hospital, an industry leading nephrology site
  • Easy access to matching healthy control subjects through a database of over 120,000 participants, 40,000 active
  • Ongoing outreach efforts to maintain and increase patient database
  • Searchable database to qualify IE criteria for pre-existing conditions, demographics, medication use, and BMI

Experience

  • Six months to complete a study for 32 patients (including all 4 stages from control to severe)
  • Assessment of dosage adjustment requirements for marketed drug products in patients with impaired renal function
  • Administration of the investigational drug at the same dosage, to groups with mild, moderate and severe renal impairment
  • Study design in accordance to FDA and EMA guidances

Clinical Expertise