The Bioanalytical Services Department offers scientific excellence, uncompromised quality and unbeatable timelines to meet and exceed client needs.
Our GLP-compliant bioanalytical facility is 20,000 sq feet (1850 sq metres), equipped with next generation instrumentation focused on addressing the increasing challenges such as metabolite identification and protein and peptide quantitation. It is fully equipped with a dedicated method development group and multiple state-of-the-art resources, ensuring a straightforward and compliant submission for any country.
Algorithme Pharma continues to develop and/or improve on methods for our extensive validated assay list. This list includes validated methods for drugs, metabolites and biomarkers in biological matrices, covering most therapeutic areas.
Our expertise, combined with our state-of-the-art instrumentation, allows us to achieve:
- Extremely low LLOQ
- Large dynamic ranges
- Analysis of multiple metabolites
- Analysis from various matrices and species
- Quick method development of high throughput assays using strict criteria
- Successful method transfer or adaptation
We are also working on methods using new and/or high throughput technologies, such as Dried Blood Spots (DBS) analysis. Through our expertise we can overcome challenges like potential stability issues and matrix effects. One of our major focuses is to develop rugged methods that are free of interference from metabolites.
We perform assays for over 400,000 samples per year, many for multiple analytes and comprising parent drug and several metabolites in one single assay. Sample analysis is performed for projects carried out in our own clinics as well as for external projects (from preclinical to Phase I-IV).