Poster Presentations
at the 2015 AAPS Meeting in Orlando:

Development and Validation of an ELISA for the Determination of AB-16B5 in Rat Serum: Application to Toxicokinetic Studies

Main Author: Fanny Bonin2

Presenting Author: Robert Masse1

Author: Mauricio Lemus2, Julie Laurin2, Lillian Mottley1, Stephen Wallace1, Patricia Rivest1, Thu Bich Vu1, Susana Liu1

1Algorithme Pharma

2Alethia Biotherapeutics, Inc.

Poster Number:
T2239

Presentation Date/Time:
October 27, 2015
8:30 AM – Noon
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Development and Validation of a Quantitative Human Plasma Endothelin-1 Chemiluminescence Immunoassay in the 0.50 to 12.50 pg/mL Range

Main Author: Farideh Nourian1

Presenting Author: Robert Masse1

Author: Victor Hugo Huerto1, Stephen Wallace1, Susana Liu1,

1Algorithme Pharma
Poster Number:
T2247

Presentation Date/Time:
October 27, 2015
8:30 AM – Noon
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An Ultrafiltration Assay for Assessing the Extent of Whole Plasma Protein-Binding of Antisense Oligonucleotides in Human and Various Species Plasma

Main Author: Martin Clement1

Presenting Author: Robert Masse1

Author: Thu Bich Vu1, Bryan Tayefeh2, Sara Greenlee2, Rosie Yu2, Tanya Watanabe2, Dan Norris2

1Algorithme Pharma
2ISIS Pharmaceuticals, Inc
Poster Number:
T2248

Presentation Date/Time:
October 27, 2015
8:30 AM – Noon
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Fed and Fasted Comparative Bioavailability Study of RHB-102 (Once-Daily Ondansetron 24 mg Extended-Release Tablets) in Healthy Volunteers

Main Author: Laura Sayegh1

Presenting Author: Julie Massicotte1

Author: Rachida Essalihi1, Eric Sicard1, Mireille Noumeir1, Marc Lefebvre1, Reza Fathi2, Terry Plasse2, Gilead Raday2

1Algorithme Pharma
2RedHill Biopharma Ltd.
Poster Number:
T2320

Presentation Date/Time:
October 27, 2015
8:30 AM – Noon
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Comparative Bioavailability Study of RHB-102 (Ondansetron 24 mg ER Tablets Qd) Versus Ondansetron 8 mg Tablets Bid and a Single Dose of Ondansetron 24 mg in Healthy Volunteers

Main Author: Laura Sayegh1

Presenting Author: Julie Massicotte1

Author: Jean-Michel Paquette1, Rachida Essalihi1, Eric Sicard1, Mireille Noumeir1, Marc Lefebvre1, Reza Fathi2 Terry Plasse2, Gilead Raday2

1Algorithme Pharma
2RedHill Biopharma Ltd.
Poster Number:
T2327

Presentation Date/Time:
October 27, 2015
8:30 AM – Noon
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Sample Extraction Methods Comparison for Multi-peptide Quantification of a PEGylated Protein by LC-MS following Rat Whole Blood Timecourse Kinetic

Main Author: Jonathan St-Germain1

Presenting Author: Jean-Nicholas Mess1

Author: Fabio Garofolo2

1Algorithme Pharma
2ACRAF-Angelini Research Center
Poster Number:
W5194

Presentation Date/Time:
October 28, 2015
1:30 PM – 5:00 PM
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Impact of Mobile Phase Modifiers and Supercharging Reagents on Charge State Distribution and Sensitivity of Therapeutic Peptides by LC-HRMS

Main and Presenting Author: Jean-Nicholas Mess1

Author: Daniel Villeneuve1, Fabio Garofolo2

1Algorithme Pharma
2ACRAF-Angelini Research Center
Poster Number:
W5195

Presentation Date/Time:
October 28, 2015
1:30 PM – 5:00 PM
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Strategy for the Quantification of a Paclitaxel Conjugated ADC (DAR ≥ 1) in Rat Plasma by LC-HRMS

Main and Presenting Author: Jean-Nicholas Mess1

Author: Fabio Garofolo2

1Algorithme Pharma
2ACRAF-Angelini Research Center
Poster Number:
W5196

Presentation Date/Time:
October 28, 2015
1:30 PM – 5:00 PM
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Application of Complementary HRMS Methodologies for a Thorough Biosimilar Comparability Assessment

Main Author: Kevork Mekhssian1

Presenting Author: Jean-Nicholas Mess1

Author: Fabio Garofolo2

1Algorithme Pharma
2ACRAF-Angelini Research Center
Poster Number:
W5203

Presentation Date/Time:
October 28, 2015
1:30 PM – 5:00 PM
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What Are the Clinical Study Planning Challenges of Driving Studies: A Case Study

Main Author: Audrey Fortier1

Presenting Author: Eric Legault1

Author: Eric Sicard1, Steven Tupper1, Marc Lefebvre1

1Algorithme Pharma
Poster Number:
R6338

Presentation Date/Time:
October 29, 2015
8:00 AM – 11:30 AM
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